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Previous Volume 352:1463-1472 April 7, 2005 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 17-year-old boy with a six-month history of acne presents for initial evaluation and treatment. Physical examination reveals closed and open comedones and a large number of erythematous papules and pustules (50 or more) of the face and upper trunk. How should he be treated?

The Clinical Problem

Acne affects more than 85 percent of teenagers but frequently continues into adulthood.¹ Although there are more . . . [Full Text of this Article]

Strategies and Evidence

Diagnosis

Therapy

            Topical Treatment

            Topical Retinoids

            Topical Antimicrobials

            Other Topical Medications

Oral Therapy

            Oral Antibiotics

            Lack of Response

            Hormonal Therapy

            Isotretinoin

            Other Forms of Therapy

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the Department of Dermatology, University of Pennsylvania, Philadelphia.

This article has been cited by other articles:

• Nader, S., Diamanti-Kandarakis, E. (2007). Polycystic ovary syndrome, oral contraceptives and metabolic issues: new perspectives and a unifying hypothesis. Hum Reprod 22: 317-322 [Abstract] [Full Text]  
• Ayer, J, Burrows, N (2006). Acne: more than skin deep.. Postgrad. Med. J. 82: 500-506 [Abstract] [Full Text]  
• Zane, L. T. (2006). Acne maintenance therapy: expanding the role of topical retinoids?. Arch Dermatol 142: 638-640 [Full Text]  
• Krowchuk, D. P. (2005). Managing Adolescent Acne: A Guide for Pediatricians. Pediatr. Rev. 26: 250-261 [Full Text]