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Previous Volume 352:1485-1487 April 7, 2005 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Laypeople and health care professionals alike recognize Staphylococcus aureus as an important cause of disease and understand that antibiotic-resistant strains pose a threat to the community. Before the availability of antibiotics, invasive staphylococcal disease was often fatal, and the introduction of penicillin in the 1940s dramatically improved survival. Although penicillinase-producing strains soon emerged, methicillin and other penicillinase-stable -lactam agents filled the breach. However, methicillin-resistant strains of S. aureus (MRSA), which are resistant to the entire class of -lactam agents, were identified almost immediately and are now found in hospitals worldwide. Despite the growing prevalence of MRSA in hospitals, these strains . . . [Full Text of this Article]

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From the Division of Infectious Diseases, San Francisco General Hospital, University of California–San Francisco, San Francisco.

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