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Previous Volume 352:1716-1718 April 21, 2005 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Chan et al. (Jan. 20 issue)¹ conclude that aspirin plus a proton-pump inhibitor is superior to clopidogrel in the prevention of recurrent ulcer bleeding. The authors of the study and Cryer, in an accompanying editorial,² state that the current American College of Cardiology–American Heart Association (ACC–AHA) guidelines, which recommend that aspirin be replaced with clopidogrel in patients who have a history of gastrointestinal complications, are harmful and that such patients should be given aspirin plus a proton-pump inhibitor.

The ACC–AHA guidelines state, "Clopidogrel should be administered to hospitalized patients who are unable to take ASA [acetylsalicylic acid] . . . [Full Text of this Article]

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