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Volume 352:1721-1722 April 21, 2005 Number 16
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Cardiovascular Risk and Body-Fat Abnormalities in HIV-Infected Adults

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 by Grinspoon, S.
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To the Editor: In their review of metabolic and cardiovascular risk factors affecting patients infected with the human immunodeficiency virus (HIV), Grinspoon and Carr (Jan. 6 issue)1 recommend the guidelines of the National Cholesterol Education Program for lipid-lowering therapy in HIV-infected patients with hyperlipidemia. Prediction of coronary heart disease (CHD) with the use of the Framingham equation, however, is based on (and principally predictive for) outpatients free of disease.2 Estimation of the 10-year risk of CHD at any point is based on the person's past and expected future lipid levels (which are best assessed as the area under the curve, . . . [Full Text of this Article]


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