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Volume 352:1817-1819 April 28, 2005 Number 17
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Alcohol and Cognitive Function in Older Women

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by Evans, D. A.
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by Stampfer, M. J.
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To the Editor: Stampfer et al. (Jan. 20 issue)1 suggest that "women who consume up to one drink per day have less cognitive impairment . . . than nondrinkers," on the basis of the authors' data from the Nurses' Health Study and findings reported in the literature. A significant limitation of the study by Stampfer et al. is its low generalizability. On the basis of their exclusion criteria, the findings are applicable only to relatively well educated women with very stable drinking patterns who have no history of antidepressant use. Furthermore, a major threat to the study's external validity appears . . . [Full Text of this Article]



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