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Some of the most exciting recent advances in immunology have been made in a field that has languished for too long: that of the innate immune system, particularly the complex web of first-response molecules that compose it. Immunologic research in the past three decades has rushed to characterize critical dichotomies in immune response such as the B and T lymphocytes, CD4 and CD8 T cells, and humoral as compared with cellular immunity whereas the investigation of innate immune pathways has proceeded at a slower (but steady) rate. Now, however, it is time for a fine book on the
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