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Previous Volume 352:2025-2026 May 12, 2005 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Kragelund and colleagues (Feb. 17 issue)¹ tested the N-terminal fragment of pro–brain natriuretic peptide (NT-pro-BNP) as a marker of long-term mortality in patients with stable coronary disease and concluded that it provides improved prognostic information as compared with conventional cardiovascular risk factors. Creatinine clearance was not found to be a significant risk factor. However, the effect of renal function should be clarified in more detail, since moderate renal impairment is well established as a strong predictor of cardiovascular disease and mortality from all causes,² and since NT-pro-BNP is primarily eliminated by the kidneys.^3,4 Increased NT-pro-BNP levels may . . . [Full Text of this Article]

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