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Previous Volume 352:207-208 January 13, 2005 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We wish to report initial success in treating a boy with surfactant protein C deficiency. The patient was first admitted to the hospital at five months of age with severe respiratory distress that followed a viral respiratory infection. Open-lung biopsy revealed nonspecific interstitial pneumonitis, and DNA analysis revealed that the gene encoding surfactant protein C had a C-to-A substitution leading to an alanine-to-aspartate substitution at amino acid 116 in exon 4. The patient was discharged home in moderate respiratory distress; he was breathing oxygen at a rate of 2 to 3 liters per minute by nasal cannula . . . [Full Text of this Article]

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