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Volume 352:209-210 January 13, 2005 Number 2
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The Skeleton: Biochemical, Genetic, and Molecular Interactions in Development and Homeostasis

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Edited by Edward J. Massaro and John M. Rogers. 428 pp., illustrated. Totowa, N.J., Humana Press, 2004. $150. ISBN 1-58829-215-0.

Because the structural role of the skeletal system is obvious, and because the hardness of mineralized bone matrix and the prolonged duration of adult bone mass emphasize its solidity, the dynamic and multifunctional nature of the skeleton are not an observer's first impression. With the World Health Organization's Decade of Bone and Joint Disease report and the 2004 U.S. Surgeon General's report on bone health and osteoporosis, we are reminded of the prevalence and cost of postmenopausal osteoporosis and fractures, cancer metastases to bone, and a host of endocrine and genetic disorders that have a primary impact on cartilage and . . . [Full Text of this Article]




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