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Previous Volume 352:2238-2239 May 26, 2005 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Colorectal cancer is a major health concern, with more than 1 million cases and half a million cancer-related deaths estimated worldwide in 2002.¹ These statistics are sobering, considering that the availability of well-established screening and surgical techniques should make most cases preventable. Colorectal cancer typically develops over a period of 10 to 20 years, providing ample time for detection and surgical or medical intervention before it poses a clinical threat. To date, our best chemopreventive interventions have been identified by a convergence of data from at least three domains — observational, in vitro, and in vivo studies. The efficacy of . . . [Full Text of this Article]

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From the Office of Centers, Training, and Resources (E.H.) and the Division of Cancer Prevention (J.L.V.), National Cancer Institute, Bethesda, Md.

Related Letters:

Statins and the Risk of Colorectal Cancer
Setoguchi S., Avorn J., Schneeweiss S., Maisonneuve P., Eng. , Lowenfels A. B., Welch H. G., Poynter J. N., Gruber S. B., Rennert G.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:952-954, Sep 1, 2005. Correspondence

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