Brucellosis, like tuberculosis, is a chronic granulomatous infectioncaused by intracellular bacteria and requires combined, protractedantibiotic treatment. The disease causes much clinical morbidityas well as a considerable loss of productivity in animal husbandryin the developing world. In this era of international tourism,brucellosis has become a common imported disease in the developedworld.
Brucellosis has been present for millennia1 and has managedto elude eradication, even in most developed countries.2,3 Ahigh prevalence in certain geographic areas is well recognized,although largely underestimated (Table 1). The relationshipbetween the disease and individual socioeconomic status is . . . [Full Text of this Article]
The Bacterium
The B. Melitensis Genome
Pathogenetic Features
The Host Response in Humans
Human Disease
Special Situations
Diagnosis
Treatment
The Future
Source Information
From the Brucellosis Unit, University Hospital of Ioannina, Ioannina, Greece.
Address reprint requests to Dr. Pappas at the Internal Medicine Department, University Hospital of Ioannina, 45110 Ioannina, Greece, or at gpele@otenet.gr.
Related Letters:
Brucellosis
Davis C. E., Troy S. B., Tonna I., Tonna A., Pappas G., Akritidis N., Tsianos E. V.
Extract |
Full Text |
PDF
N Engl J Med 2005;
353:1071-1072, Sep 8, 2005.
Correspondence
This article has been cited by other articles:
Turunc, T., Demiroglu, Y. Z., Aliskan, H., Colakoglu, S., Timurkaynak, F., Ozdemir, N., Arslan, H.
(2008). Brucellosis in cases of end-stage renal disease. Nephrol Dial Transplant
23: 2344-2349
[Abstract][Full Text]
Zachou, K., Papamichalis, P. A., Dalekos, G. N.
(2008). Severe pharyngitis in stockbreeders: an unusual presentation of brucellosis. Occup Med (Lond)
58: 305-307
[Abstract][Full Text]
Pappas, G.
(2008). Treatment of brucellosis. BMJ
336: 678-679
[Full Text]
Skalsky, K., Yahav, D., Bishara, J., Pitlik, S., Leibovici, L., Paul, M.
(2008). Treatment of human brucellosis: systematic review and meta-analysis of randomised controlled trials. BMJ
336: 701-704
[Abstract][Full Text]
Queipo-Ortuno, M. I., De Dios Colmenero, J., Macias, M., Bravo, M. J., Morata, P.
(2008). Preparation of Bacterial DNA Template by Boiling and Effect of Immunoglobulin G as an Inhibitor in Real-Time PCR for Serum Samples from Patients with Brucellosis. CVI
15: 293-296
[Abstract][Full Text]
Navarro-Martinez, A., Navarro, E., Castano, M. J., Solera, J.
(2008). Rapid Diagnosis of Human Brucellosis by Quantitative Real-Time PCR: a Case Report of Brucellar Spondylitis. J. Clin. Microbiol.
46: 385-387
[Abstract][Full Text]
Copin, R., De Baetselier, P., Carlier, Y., Letesson, J.-J., Muraille, E.
(2007). MyD88-Dependent Activation of B220-CD11b+LY-6C+ Dendritic Cells during Brucella melitensis Infection. J. Immunol.
178: 5182-5191
[Abstract][Full Text]
Mitka, S., Anetakis, C., Souliou, E., Diza, E., Kansouzidou, A.
(2007). Evaluation of Different PCR Assays for Early Detection of Acute and Relapsing Brucellosis in Humans in Comparison with Conventional Methods. J. Clin. Microbiol.
45: 1211-1218
[Abstract][Full Text]
Le Monnier, A., Autret, N., Join-Lambert, O. F., Jaubert, F., Charbit, A., Berche, P., Kayal, S.
(2007). ActA Is Required for Crossing of the Fetoplacental Barrier by Listeria monocytogenes. Infect. Immun.
75: 950-957
[Abstract][Full Text]
Rabinowitz, R., Shneck, M., Levy, J., Lifshitz, T.
(2006). Ocular Brucellosis vs Vogt-Koyanagi-Harada Syndrome--Reply. Arch Ophthalmol
124: 609-609
[Full Text]
Le Monnier, A., Join-Lambert, O. F., Jaubert, F., Berche, P., Kayal, S.
(2006). Invasion of the Placenta during Murine Listeriosis. Infect. Immun.
74: 663-672
[Abstract][Full Text]
Davis, C. E., Troy, S. B., Tonna, I., Tonna, A., Pappas, G., Akritidis, N., Tsianos, E. V.
(2005). Brucellosis. NEJM
353: 1071-1072
[Full Text]
Previous
