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Previous Volume 352:2325-2336 June 2, 2005 Number 22 Next

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Brucellosis, like tuberculosis, is a chronic granulomatous infection caused by intracellular bacteria and requires combined, protracted antibiotic treatment. The disease causes much clinical morbidity as well as a considerable loss of productivity in animal husbandry in the developing world. In this era of international tourism, brucellosis has become a common imported disease in the developed world.

Brucellosis has been present for millennia¹ and has managed to elude eradication, even in most developed countries.^2,3 A high prevalence in certain geographic areas is well recognized, although largely underestimated (Table 1). The relationship between the disease and individual socioeconomic status is . . . [Full Text of this Article]

The Bacterium

The B. Melitensis Genome

Pathogenetic Features

The Host Response in Humans

Human Disease

Special Situations

Diagnosis

Treatment

The Future

Source Information

From the Brucellosis Unit, University Hospital of Ioannina, Ioannina, Greece.

Address reprint requests to Dr. Pappas at the Internal Medicine Department, University Hospital of Ioannina, 45110 Ioannina, Greece, or at gpele@otenet.gr.

Related Letters:

Brucellosis
Davis C. E., Troy S. B., Tonna I., Tonna A., Pappas G., Akritidis N., Tsianos E. V.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:1071-1072, Sep 8, 2005. Correspondence

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