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Correspondence
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Volume 352:2357-2358 June 2, 2005 Number 22
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Correction of Factor XI Deficiency by Liver Transplantation

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To the Editor: Liver transplantation is considered to be an appropriate therapeutic option for hemophilia complicated by cirrhosis.1 Correction of deficiencies of factor VIII and factor IX by liver transplantation is well known.2 Factor XI deficiency is a less common form of hemophilia that is associated with prolonged bleeding during surgery, rather than with spontaneous hemorrhage, as is seen in patients with hemophilia A or B. Correction of factor XI deficiency by liver transplantation has not been reported, to our knowledge.

Recently, we performed a liver transplantation in a 48-year-old man with hepatitis C virus (HCV) cirrhosis and hepatocellular carcinoma . . . [Full Text of this Article]



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