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Previous Volume 352:2360-2361 June 2, 2005 Number 22 Next

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Edited by Ron Waksman and Patrick W. Serruys. 418 pp., illustrated. London, Taylor & Francis, 2004. $69.95. ISBN 1-84184-323-7.

Angiographic observations in the early 1980s confirmed that acute coronary thrombosis was the proximate cause of acute myocardial infarction — seminal studies that led to revolutionary treatments for the recanalization of occluded vessels. However, during the subsequent decades, the results of basic and clinical investigation have shown that the coronary clot is predominantly a secondary phenomenon; the true culprit in unstable ischemic heart disease is rupture of the underlying vulnerable atherosclerotic plaque.

(Figure)

View larger version (44K): [in this window] [in a new window]   Color-Enhanced Photomicrograph of an Artery with Plaque. Wellcome Photo Library.

 
Handbook of the Vulnerable Plaque was edited by two distinguished leaders in interventional cardiology, Patrick . . . [Full Text of this Article]

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