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The association between thrombosis and cancer represents a challenge to scientists and physicians of various disciplines. From a clinician's point of view, progress in this field during the past several years has been substantial. In a patient presenting with venous thrombosis who is otherwise healthy, for example, the likelihood that there is a hidden cancer is now well defined, and we have estimates of the risk of thrombosis among patients with cancer who are exposed to surgery, chemotherapy, or the insertion of a central venous catheter. With the development of new antithrombotic drugs, particularly the low-molecular-weight heparins, preventive and therapeutic
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