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Previous Volume 352:2645-2646 June 23, 2005 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Despite its isolation three decades ago, Ebola virus continues to cause periodic outbreaks of severe hemorrhagic fever in humans, and the closely related Marburg virus is responsible for a recent outbreak of disease in Angola. The mortality rate associated with Ebola virus infection can reach 90 percent, and so the prospect of an effective therapy is attractive. A recent study by Chandran et al.¹ sheds light on the molecular events that culminate in infection and may thus lead to a new approach to therapy.

Embedded within the host-derived lipid envelope of Ebola virus are glycoprotein spikes that bind to cells . . . [Full Text of this Article]

Source Information

From the International Research Center for Infectious Diseases and the Division of Virology, the Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo; and the Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin–Madison, Madison.

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