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Correspondence
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Volume 352:2650-2651 June 23, 2005 Number 25
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Morphine, Gabapentin, or Their Combination for Neuropathic Pain

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 by Gilron, I.
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To the Editor: The cleverly designed and carefully conducted crossover trial reported by Gilron et al. (March 31 issue)1 shows better control of neuropathic pain with the combination of morphine and gabapentin than with single agents or placebo. Although we admire the meticulousness of the investigators, we also marvel at the unusually rigid adherence of the majority of the patients to a demanding and complex drug regimen. We must conclude that this was a very select group of highly motivated and fastidious patients. It is likely that they had many more personality traits in common with one another than with . . . [Full Text of this Article]


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