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Previous Volume 352:2714-2720 June 30, 2005 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 60-year-old woman who quit smoking 20 years earlier comes for a routine visit. She previously smoked one pack of cigarettes a day for 10 years. Her medical history is otherwise unremarkable. She feels well and exercises regularly. Her husband smoked one pack of cigarettes per day for at least 30 years but stopped smoking a decade ago. She asks whether she . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Limitations of the Available Studies

Risks of Screening

Randomized Clinical Trials

Areas of Uncertainty

Benefits of Screening

Effect of Advancing Technology

Management of Small Cancers Detected by Screening

Costs and Cost-Effectiveness

Guidelines from Professional Societies

Summary and Recommendations

Source Information

From the Intervention Section, Cell and Cancer Biology Branch, Lung Cancer and Aerodigestive Chemoprevention Faculty, Center for Cancer Research, National Cancer Institute, Bethesda, Md. (J.L.M.); and the Cancer Imaging Program, Division of Cancer Treatment and Diagnosis, National Cancer Institute, Rockville, Md. (D.C.S.).

Address reprint requests to Dr. Mulshine at the National Institutes of Health Clinical Center, Rm. 12N226, Cell and Cancer Biology Branch, Bethesda, MD 20892, or at mulshinj@mail.nih.gov.

Related Letters:

Lung-Cancer Screening
Reich J. M., Mulshine J. L., Sullivan D. C.
Extract | Full Text | PDF  
N Engl J Med 2005; 353:2194-2195, Nov 17, 2005. Correspondence

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