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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 47-year-old woman with a history of breast cancer presents with confusion and dehydration. The serum calcium level is 18.0 mg per deciliter (4.5 mmol per liter). She has postural hypotension and low central venous pressure on examination of the jugular veins. The serum phosphorus level is 5.0 mg per deciliter (1.6 mmol per liter), the blood urea nitrogen level is 80.0
The Clinical Problem
Strategies and Evidence
Diagnosis
Therapeutic Considerations
General Supportive Measures
Saline Hydration and Calciuresis
Medications
Other Pharmacologic Agents
Dialysis
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Division of Endocrinology, University of Pittsburgh School of Medicine, Pittsburgh.
Address reprint requests to Dr. Stewart at the Division of Endocrinology and Metabolism, BST E-1140, University of Pittsburgh School of Medicine, 200 Lothrop St., Pittsburgh, PA 15213, or at stewart@dom.pitt.edu.
This article has been cited by other articles:
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