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Previous Volume 352:425 January 27, 2005 Number 4

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Edited by W. Hamish B. Wallace and Daniel M. Green. 416 pp., illustrated. London, Arnold, 2004. $149.50. ISBN 0-340-80803-9.

Modern therapy for childhood cancer is a double-edged sword. With judicious combinations of chemotherapy, radiotherapy, and surgery, as well as supportive care, physicians can design treatment protocols that will secure long-term disease-free survival in at least 70 percent of children with cancer. Most of these patients will enjoy normal lives, yet a sizable proportion will experience major and sometimes debilitating complications. Thus, further efforts to improve cure rates must be tempered by knowledge of the risks and the spectrum of treatment-related sequelae. Although numerous journal articles have dealt with particular aspects of the late effects of treatment for childhood cancer, . . . [Full Text of this Article]

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