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Previous Volume 352:509-511 February 3, 2005 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In the study reported by Sauer et al. (Oct. 21 issue),¹ 18 percent of the patients in the postoperative-chemoradiotherapy group were found to have stage I disease, and about 10 percent were found intraoperatively to have distant metastases or other complications. Because of the randomized assignment to treatment, it is reasonable to assume that there were similar percentages of patients with stage I and stage IV disease — patients who were not likely to derive any benefit from chemoradiotherapy — in the preoperative group. The authors' suggestion that preoperative chemoradiotherapy may be the preferred treatment would subject . . . [Full Text of this Article]

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