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Volume 352:536-538 February 10, 2005 Number 6
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Myelodysplastic Syndromes — Coping with Ineffective Hematopoiesis
Mario Cazzola, M.D., and Luca Malcovati, M.D.

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 by List, A.
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One of the most challenging problems in hematology is the heterogeneous group of disorders that were formally defined as myelodysplastic syndromes by the French–American–British Cooperative Group in 1982. This set of disorders includes idiopathic conditions as well as the secondary or therapy-related forms that develop after exposure to alkylating agents, radiation, or both. Idiopathic myelodysplastic syndromes occur mainly in older persons: the incidence of these syndromes is about 5 per 100,000 persons per year in the general population, but it increases to 20 to 50 per 100,000 persons per year after 60 years of age. Approximately 15,000 new cases are . . . [Full Text of this Article]


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Dr. Cazzola is a professor of hematology and Dr. Malcovati a senior fellow at the University of Pavia Medical School, Pavia, Italy. Dr. Cazzola is an attending physician at the Division of Hematology, Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Matteo, Pavia, Italy.


Related Letters:

Treatment of Myelodysplastic Syndromes
Chng W. J., Stadler M., Ganser A., List A. F., Cazzola M., Malcovati L.
Extract | Full Text | PDF  
N Engl J Med 2005; 352:2134-2135, May 19, 2005. Correspondence

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