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Previous Volume 352:728-731 February 17, 2005 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The article by Aharon-Peretz et al. (Nov. 4 issue)¹ is of considerable interest to us because it substantiates our previously published study² in which glucocerebrosidase mutations were identified in brain samples from patients with parkinsonism. Autopsy samples from 57 patients with pathologically confirmed Parkinson's disease and 44 controls were screened by sequencing the entire glucocerebrosidase gene. Eight samples from the patients (14 percent) had glucocerebrosidase mutations, as compared with none of the samples from the control group. In addition, we recently sequenced 26 brain samples (from the U.K. Parkinson's Disease Society Tissue Bank at Imperial College, London) . . . [Full Text of this Article]

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