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Volume 352:738-739 February 17, 2005 Number 7
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Epilepsy: Scientific Foundations of Clinical Practice

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(Neurological Disease and Therapy. Vol. 64.) Edited by Jong M. Rho, Raman Sankar, and José E. Cavazos. 510 pp., illustrated. New York, Marcel Dekker, 2004. $165. ISBN 0-8247-5043-8.

Progress in epilepsy research during the past several decades has advanced our understanding of the disease and greatly expanded our choice of treatments. Research in molecular and cellular biology has improved our understanding of the pathologic changes that ensue during a latent period, eventually giving rise to seizures. This understanding, in turn, has served as the basis for the development of effective therapies. Despite exciting scientific discoveries, however, there is a disconnect between bench research and clinical practice. For the most part, the clinical-practice aspect remains largely empirical in the general neurology community.

There is no question that the types . . . [Full Text of this Article]




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