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Volume 352:846 February 24, 2005 Number 8
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Microbial Biofilms

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Edited by Mahmoud Ghannoum and George A. O'Toole. 426 pp., illustrated. Washington, D.C., ASM Press, 2004. $115.95. ISBN 1-55581-294-5.

Since the discovery of microorganisms several hundred years ago, our study of the microbial world has largely concentrated on characterization of planktonic (free-living) organisms. Adherence to Koch's postulates and the use of standard microbiologic culture techniques have allowed us to understand and successfully control many acute epidemic infectious diseases. However, more recently, there is an increasing appreciation that planktonic microbes account for only a very small proportion of microbial life, and in both natural environments and human disease, the bulk of microbes are found in a sessile form in biofilms.

A biofilm is a community of microorganisms that are associated . . . [Full Text of this Article]


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