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Correspondence
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Volume 352:935-937 March 3, 2005 Number 9
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Umbilical-Cord Blood for Transplantation in Adults

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by Laughlin, M. J.
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by Rocha, V.
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To the Editor: The low rates of survival among adults who received cord-blood transplants in the two observational studies reported by Laughlin et al. and Rocha et al. (Nov. 25 issue)1,2 are not representative of what is being achieved nowadays with these transplants.3,4,5 Toxic effects and infections related to a slow rate of hematopoietic recovery appear to be the main factors in early transplant-related mortality and deterrents to successful cord-blood transplantation in adults. "Novel strategies to overcome this obstacle are needed," conclude Laughlin et al.

We think the strategy we have developed fulfills this need4: low-toxicity myeloablative conditioning and . . . [Full Text of this Article]



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