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Volume 353:93-96 July 7, 2005 Number 1
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Intensive Lipid Lowering with Atorvastatin in Coronary Disease

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 by Pitt, B.
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 by LaRosa, J. C.
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To the Editor: LaRosa and colleagues (April 7 issue)1 report that among patients with stable coronary heart disease (CHD), an intensive statin regimen provides a 22 percent reduction in the risk of cardiovascular events when compared with a standard regimen. However, despite the 20 percent reduction in the risk of death from CHD in the group that received 80 mg of atorvastatin per day, there was no significant difference between the groups in overall mortality. This finding reflects an increase in the risk of death from noncardiovascular causes, which is undoubtedly a matter of concern.

In patients with an acute . . . [Full Text of this Article]


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