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Volume 353:1294-1297 September 22, 2005 Number 12
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Sudden Death in Patients with Myocardial Infarction

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by Buxton, A. E.
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by Solomon, S. D.
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To the Editor: Solomon and colleagues (June 23 issue)1 report that in the Valsartan in Acute Myocardial Infarction Trial (VALIANT), 19 percent of patients with heart failure, left ventricular dysfunction, or both, after myocardial infarction who died suddenly from cardiac causes or had cardiac arrest with resuscitation did so within the first 30 days after infarction. In the Eplerenone Post–Acute Myocardial Infarction Heart Failure Efficacy and Survival Study (EPHESUS),2 involving patients with both heart failure and left ventricular dysfunction (an ejection fraction of ≤40 percent) after myocardial infarction, my colleagues and I recently found that there was a similar high, . . . [Full Text of this Article]



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