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On the basis of the title of this book, the reader may wonder if the intent is to develop a theory of multiple sclerosis as a primary axonal disease, as some investigators have suggested. Actually, the editor writes in the preface that "the title . . . is not meant to imply that MS is a primary neuronal disease." Instead, most of the chapters focus on a detailed examination of the biology of the axon, measures that can be used to identify axonal damage, mechanisms that may lead to axonal damage, and some approaches to protection or repair.
As with
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