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Previous Volume 353:1398-1400 September 29, 2005 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Sepsis, severe sepsis, and septic shock represent a spectrum of increasingly severe diseases that result from serious infection and the body's response to microbiologic invasion. Population data suggest that 750,000 cases of severe sepsis occur in the United States annually; this illness is responsible for as many deaths as acute myocardial infarction (215,000, or 9.3 percent of deaths from all causes).^1,2,3 Almost every discipline in medicine must deal with this disease, from neonatology to orthopedic surgery to emergency medicine, though much of the management is performed by critical care physicians in intensive care units.

The pathogenic mechanisms underlying severe sepsis . . . [Full Text of this Article]

Source Information

From the Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, and Cooper University Hospital — all in Camden, New Jersey.

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