The remarkable reduction of 50 percent or more in the age-adjustedmortality rate from coronary heart disease over the past fourdecades in the United States1 has been driven by three parallelphenomena: an understanding of the risk factors that influencethe likelihood and presentation of coronary events, the useof randomized trials to create an indisputable evidence baseon which to make decisions, and the flexibility to change systemsof care to incorporate new knowledge into practice. Despitethe failure of some physicians to adopt proven interventions2and substantial disparities in the U.S. health care system,3the reduction in . . . [Full Text of this Article]
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From the Department of Medicine, University of California, San Francisco, San Francisco.
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Medicare and Cost-Effectiveness Analysis
Schulman K. A., Smolkin M. T., Berger M., Honig P., Spatz I., Neumann P. J., Rosen A. B., Weinstein M. C., Goldman L.
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N Engl J Med 2006;
354:207-209, Jan 12, 2006.
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