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The rapid progress in our understanding of the fundamental mechanisms of neoplasia and the pace of discovery in diagnostics and therapeutics in malignant hematology present great challenges for publishers and editors of hematology textbooks. Chapters that are on the cutting edge at the time of publication may seem dated very rapidly. As a source of current clinical concepts, the published textbook cannot compete with Web-based clinical reviews, which can be updated frequently to incorporate emerging knowledge. However, a broad-based textbook can still have an important role, synthesizing and providing perspective regarding established and emerging clinical and scientific concepts. This has
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