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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
As part of a routine examination for insurance coverage, a 25-year-old previously healthy woman is found to have a positive test for human immunodeficiency virus type 1 (HIV-1) antibody. Heterosexual contact is her only risk factor for HIV acquisition. She is asymptomatic and has a normal physical examination. The results of hematologic and other routine laboratory tests are normal. Her CD4 cell
The Clinical Problem
Strategies and Evidence
Screening for HIV Infection
Testing and Counseling
Evaluation of the Patient
Prophylaxis against Opportunistic Infections
Initiation of Antiretroviral Therapy
Treatment Regimen
Areas of Uncertainty
Guidelines from Professional Societies
Conclusions and Recommendations
Source Information
From the Division of Infectious Diseases, Columbia University Medical Center, New York.
Address reprint requests to Dr. Hammer at the Division of Infectious Diseases, Columbia University Medical Center, 630 W. 168th St., PH 8 West, Room 876, New York, NY 10032, or at smh48@columbia.edu.
Related Letters:
Newly Diagnosed HIV Infection
Chin-Hong P. V., Hecht F. M., Klausner J. D., Hammer S. M.
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N Engl J Med 2006;
354:771-772, Feb 16, 2006.
Correspondence
This article has been cited by other articles:
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