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Correspondence
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Volume 353:1856-1858 October 27, 2005 Number 17
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Benign Breast Disease and Breast Cancer

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by Elmore, J. G.
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by Hartmann, L. C.
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To the Editor: The article on the risk of cancer in patients with benign breast disease by Hartmann et al. (July 21 issue)1 contains some questionable assumptions. "Atypical ductal hyperplasia" and "lobular hyperplasia," shown in Figure 1E and Figure 1F of the article, do not belong in the category of benign breast disease. Experienced pathologists know that the differentiation of the so-called atypical ductal hyperplasia from an intraductal carcinoma of the breast is extremely difficult in most cases and impossible in some.2 Lobular hyperplasia, shown in Figure 1F, is closely related to lobular carcinoma in situ, recognized for generations as . . . [Full Text of this Article]



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