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Volume 353:1858-1860 October 27, 2005 Number 17
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Atorvastatin in Patients with Type 2 Diabetes Mellitus Undergoing Dialysis

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by Wanner, C.
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To the Editor: Wanner et al. (July 21 issue)1 report a lack of benefit from therapy with 20 mg of atorvastatin among patients with type 2 diabetes mellitus who were receiving hemodialysis, despite a high rate of cardiovascular events. In their discussion, the authors do not consider the possibility that this lack of benefit may have been related to a lack of appropriate exposure to statin therapy: approximately 50 percent of patients were no longer on the drug after two years of follow-up, and the rates for an average of four years of follow-up were not provided, though clearly even . . . [Full Text of this Article]



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