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A correction has been published: N Engl J Med 2005;353(23):2523.

Editorial
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Volume 353:2070-2073 November 10, 2005 Number 19
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Sleep — A New Cardiovascular Frontier
Virend K. Somers, M.D., Ph.D.

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Sleep occupies a third of our lives. The cardiovascular implications of normal and disturbed sleep, and of sleep apnea1 in particular, have only recently gained prominence. Central sleep apnea is characterized by intermittent loss of respiratory drive, resulting in apnea followed by compensatory periods of hyperventilation. Obstructive sleep apnea occurs when mechanisms that maintain upper-airway tone during sleep are dysfunctional, resulting in a narrowing or collapse of the airway. Obstructive sleep apnea is often treatable by some combination of postural change, weight loss, and therapy with continuous positive airway pressure (CPAP); treatment paradigms for central sleep apnea are less clear. . . . [Full Text of this Article]


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From the Department of Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minn.


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