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Editorial
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Volume 353:2285-2287 November 24, 2005 Number 21
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Antioxidant Therapy for Idiopathic Pulmonary Fibrosis
Gary W. Hunninghake, M.D.

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-Related Article
 by Demedts, M.
-PubMed Citation
Idiopathic pulmonary fibrosis (IPF) is a progressive disease characterized by fibrosis and remodeling of the lung parenchyma. The median survival of patients with the disease is about three years after diagnosis or five years after the onset of symptoms. The pathological findings are those of usual interstitial pneumonia.1 In many instances, the diagnosis can be made when typical clinical and radiologic features are present.2,3,4,5 The classic radiologic features are a patchy pattern of peripheral "honeycombing" that is more prominent in the bases of the lungs, traction bronchiectasis, and the absence of prominent ground-glass opacity. When these findings are not present, . . . [Full Text of this Article]


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From the Department of Medicine, University of Iowa and Veterans Affairs Medical Center, Iowa City.


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