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Volume 353:2428-2431 December 8, 2005 Number 23
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Remembering Berton Roueché — Master of Medical Mysteries
Barron H. Lerner, M.D., Ph.D.

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"He was never going to sleep again. Sleep was a waste of time. Then he got the idea I was trying to poison him. He didn't trust me, he said, and if I didn't leave him alone, he would tear off his clothes and run out in the street naked."1

Fifty years ago, these words taught the public about a horrifying side effect of the new "wonder drug" cortisone: mania. The speaker was the wife of a man who had been treated with cortisone for his previously incurable periarteritis nodosa, and the author quoting her was Berton Roueché, who wrote . . . [Full Text of this Article]


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Dr. Lerner is an associate professor of medicine and public health at Columbia University, New York.



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