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Correspondence
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Volume 353:2516 December 8, 2005 Number 23
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Case 28-2005: A Case of Systemic Necrotizing Vasculitis

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by Wolf, M.
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To the Editor: In Case 28-2005 (Sept. 15 issue),1 the authors describe a 42-year-old man who had a systemic necrotizing vasculitis secondary to the Churg–Strauss syndrome with rapidly progressive glomerulonephritis (with a serum creatinine level of 5.7 mg per deciliter at admission), systemic symptoms, eosinophilia, asthma, hemoptysis, sinusitis, purpura, and peripheral-nerve disease. The patient was successfully treated with corticosteroids and oral cyclophosphamide, with normalization of the serum creatinine level, erythrocyte sedimentation rate, urine sediment, and blood eosinophil count. The patient felt well, he was able to return to work, and tests for antineutrophil cytoplasmic antibodies became negative. Yet the patient . . . [Full Text of this Article]



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