Oral contraceptives were introduced into clinical practice inthe 1960s. The "pill," as this method of contraception was quicklydubbed, was touted for its ease of administration and effectiveness.The subsequent wide use of oral contraceptives provided womenwith invaluable reproductive choices and social opportunities.1As a result, the pill has been called one of the most sociallyimportant advances of the modern medical era.2 Yet for patientswith systemic lupus erythematosus, there has been an implicitmoratorium on prescribing these medications because of concernsthat exogenous estrogens could potentially exacerbate diseasesymptoms.