The arguments in favor of the registration of clinical trialsare now familiar.1,2,3,4 Chief among these addresses the practiceof selective reporting, whereby negative or detrimental studiesare not brought into the public domain, which experts on thesubject of clinical trials consider an important form of scientificmisconduct.5 This practice, as illustrated in a number of high-profileexamples, have increased the demand for the mandatory publicregistration of clinical trials. Registration of trials shouldimprove the completeness, reliability, and quality of the interpretationof clinical research.
This need for registration prompts the question of where trialsshould be registered. . . . [Full Text of this Article]
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From the Journal of the Norwegian Medical Association, Oslo (C.H.); the Nordic Cochrane Centre, Copenhagen (P.C.G.); and the Journal of the Danish Medical Association, Copenhagen (T.V.S.).
Related Letters:
Clinical Trials Report Card
Feczko J., Johnson K., Lassere M., Krall R. L., Rockhold F., Tamir O., Lipschitz Y., Shemer J., Reidenberg M. M., Zarin D. A., Tse T., Ide N. C., Drazen J. M., Wood A. J.J., Haug C., Gøtzsche P. C., Schroeder T. V.
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N Engl J Med 2006;
354:1426-1429, Mar 30, 2006.
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