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Editorial
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Volume 353:300-302 July 21, 2005 Number 3
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Gastric Bypass and Nesidioblastosis — Too Much of a Good Thing for Islets?
David E. Cummings, M.D.

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 by Service, G. J.
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As the obesity pandemic continues to worsen and medical interventions remain only moderately effective, bariatric surgery is at present the only method that reliably results in major, long-term weight loss.1,2 The most successful procedures durably reduce body weight by about one third and ameliorate nearly all obesity-related complications, most notably — almost miraculously — type 2 diabetes mellitus.2 Not surprisingly, bariatrics is the fastest-growing surgical subspecialty. The number of bariatric surgeons registered with the American Society for Bariatric Surgery increased by almost 50 percent per year during the past several years, and the number of bariatric operations nearly doubles annually.3 . . . [Full Text of this Article]


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From the Department of Medicine, Division of Metabolism, Endocrinology, and Nutrition, University of Washington, and Veterans Affairs Puget Sound Health Care System, Seattle.


Related Letters:

Hyperinsulinemic Hypoglycemia with Nesidioblastosis after Gastric-Bypass Surgery
Carpenter T., Trautmann M. E., Baron A. D., Kaiser A. M., Service F. J., Thompson G. B., Lloyd R. V., Cummings D. E., Shannon M. H., Carlson M. J.
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N Engl J Med 2005; 353:2192-2194, Nov 17, 2005. Correspondence

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