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Editorial
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Volume 353:516-517 August 4, 2005 Number 5
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Problem Solved? West Nile Virus and Transfusion Safety
Lyle R. Petersen, M.D., M.P.H., and Jay S. Epstein, M.D.

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In 2002, just three years after its appearance in the Western Hemisphere, West Nile virus caused the largest outbreak of arboviral encephalitis ever recorded in the United States.1 Epidemiologic investigations that year revealed that West Nile virus could be transmitted by blood transfusion,2 and mathematical models suggested that hundreds of transmissions had occurred.3 By July 2003, shortly before a second seasonal outbreak of similar magnitude began, collaborations among blood-collection organizations, test-kit manufacturers, and government agencies culminated in near-universal screening of U.S. blood donations for West Nile virus with the use of newly developed nucleic acid amplification tests.

In this issue . . . [Full Text of this Article]


Source Information

From the National Center for Infectious Diseases, Centers for Disease Control and Prevention, Fort Collins, Colo. (L.R.P.); and the Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, Md. (J.S.E.).


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