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Previous Volume 353:848-850 August 25, 2005 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Schön and Boehncke (May 5 issue)¹ did not comment on the important relationship between psychological stress and psoriasis. People affected with psoriasis may have substantial stress from the manifestations of the disease as well as a high prevalence of anxiety, depression, and anger; however, stressful life events can initiate or exacerbate psoriasis in as many as 60 percent of cases.²

Endogenous corticosteroids released during psychological stress may increase vascular permeability and modulate leukocyte trafficking between the blood and other immune compartments, and norepinephrine may enhance the inflammatory process through an adjuvant effect on the functions of skin . . . [Full Text of this Article]

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