{gamma}-Hydroxybutyric Acid in Hair

doi:10.1056/NEJMc053116

Volume 354:96-97		January 5, 2006		Number 1

${gamma}$ -Hydroxybutyric Acid in Hair

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To the Editor: The review (June 30 issue)¹ on ${gamma}$ -hydroxybutyricacid (GHB) generated correspondence (Oct. 13 issue),² whichrevealed that biochemical genetics laboratories can detect GHB.²There is an additional detection method worth noting.

When a medicolegal issue is present (e.g., a drug-facilitatedcrime), finding a hard-to-detect drug can be important.³ GHBhas amnesic properties³ and is fully and rapidly metabolizedto carbon dioxide and water. Even succinic acid, a product ofGHB metabolism, becomes undetectable in urine within hours ofingestion.

However, the GHB in the body of a crime victim is still present,even after it has been . . . [Full Text of this Article]

Related Letters:

${gamma}$ -Hydroxybutyric Acid
Sass J. O., Superti-Furga A., Ringel E. R., Addolorato G., Gasbarrini G., Zvosec D. L., Smith S. W.
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N Engl J Med 2005; 353:1632-1633, Oct 13, 2005. Correspondence