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Previous Volume 354:1305-1307 March 23, 2006 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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My recent use of that august medical search engine, Google, revealed a publication that identified sin as the cause of depression. Initial amusement quickly gave way to the sobering recognition that this simplistic formulation conveyed a prevalent, if generally unarticulated, belief that depression is not a real illness but, rather, the result of a personal failing — moral, spiritual, or adaptational. How did depression come to be viewed in so pejorative a manner?

Depression certainly cannot be dismissed as rare; its lifetime prevalence is 15 to 20 percent¹ (as compared, for example, with a 4 to 6 percent lifetime prevalence . . . [Full Text of this Article]

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From the University of North Carolina, Chapel Hill.

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Depression — Augmentation or Switch after Initial SSRI Treatment
Sussman N., Williams S. C., Tebartz van Elst L., Ebert D., Hesslinger B., Rush A. J., Trivedi M. H., Wisniewski S. R., the STAR*D trial investigators , Rubinow D. R.
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N Engl J Med 2006; 354:2611-2613, Jun 15, 2006. Correspondence

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