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Previous Volume 354:1524-1527 April 6, 2006 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by The Fifth Organization to Assess Strategies in Acute Ischemic Syndromes Investigators Related Article by Antman, E. M. PubMed Citation

Acute coronary syndromes, defined as myocardial infarction with ST-segment elevation, myocardial infarction without ST-segment elevation, and unstable angina, share a common pathophysiology: atherosclerotic plaque rupture, erosion, or both with superimposed intracoronary thrombosis, commonly known as atherothrombosis.¹ Two large randomized trials reported in this issue of the Journal^2,3 address the evolving use of antithrombotic agents for these syndromes; a third trial has been published recently.⁴

Table 1 places these trials in the context of existing practice guidelines for antithrombotic agents. The oldest antithrombotic agent is unfractionated heparin. Although treatment with unfractionated heparin is generally indicated for 24 to 48 hours in . . . [Full Text of this Article]

Source Information

From the Mayo Clinic College of Medicine, Rochester, Minn. (R.J.G.); and Mt. Sinai School of Medicine, New York (V.F.).

This article was published at www.nejm.org on March 14, 2006.

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