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Volume 354:1639-1641 April 13, 2006 Number 15
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Rescue Angioplasty after Thrombolysis

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 by Gershlick, A. H.
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To the Editor: Gershlick et al. (Dec. 29 issue)1 report that emergency percutaneous coronary intervention (rescue PCI) for failed thrombolysis results in a statistically significant reduction in major cardiac and cerebrovascular events as compared with conservative treatment. In fact, there was a significant reduction only in the rate of myocardial infarction, and this result was based on very few events (12 in the conservative-treatment group and 3 in the PCI group). Even this finding may be spurious, since there are features of the trial design that may have led to bias. The use of intravenous heparin in the conservative-treatment group . . . [Full Text of this Article]




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