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Previous Volume 354:1947-1949 May 4, 2006 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Hyperbilirubinemia is the most common condition requiring evaluation and treatment of newborns, but for the vast majority of neonates, it is a benign, transitional phenomenon of no overt clinical significance. In a few infants, however, serum bilirubin may rise to hazardous levels that pose a direct threat of brain damage. Acute bilirubin encephalopathy, an uncommon disorder,¹ may ensue, frequently evolving into kernicterus, a devastating chronic disabling condition characterized by the clinical tetrad of choreoathetoid cerebral palsy, central neural hearing loss, palsy of the vertical gaze, and tooth enamel hypoplasia as the result of bilirubin-induced cell toxicity.²

Originally described in newborns . . . [Full Text of this Article]

Source Information

From the Division of Newborn Medicine, Department of Pediatrics, University of Pittsburgh School of Medicine, and the Magee–Womens Research Institute — both in Pittsburgh.

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