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Volume 354:2208-2211 May 25, 2006 Number 21
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Lymphocytic Choriomeningitis Virus — An Old Enemy up to New Tricks
C.J. Peters, M.D.

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 by Fischer, S. A.
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Lymphocytic choriomeningitis virus (LCMV) was among the first human pathogenic viruses to be isolated. In the mid-1930s, Armstrong and Lillie obtained a filterable agent thought to be from the brain of a man who died during an epidemic of St. Louis encephalitis, Traub discovered a chronic infection in a mouse colony, and Rivers and Scott isolated a virus from the cerebrospinal fluid of patients with aseptic meningitis (see image).1 All three of these viruses were shown to have the same properties and serologic features, and LCMV became the type species characterizing the virus family Arenaviridae, established in 1970. In . . . [Full Text of this Article]


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Dr. Peters is a professor of tropical and emerging virology and director of biodefense at the Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston.


Related Letters:

LCMV Transmission by Organ Transplantation
Barton L. L., Sauter C., Sauter B. V., Peters C.J.
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N Engl J Med 2006; 355:1737-1738, Oct 19, 2006. Correspondence

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