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FOCUS ON RESEARCH Previous Volume 354:2208-2211 May 25, 2006 Number 21 Next

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Lymphocytic choriomeningitis virus (LCMV) was among the first human pathogenic viruses to be isolated. In the mid-1930s, Armstrong and Lillie obtained a filterable agent thought to be from the brain of a man who died during an epidemic of St. Louis encephalitis, Traub discovered a chronic infection in a mouse colony, and Rivers and Scott isolated a virus from the cerebrospinal fluid of patients with aseptic meningitis (see image).¹ All three of these viruses were shown to have the same properties and serologic features, and LCMV became the type species characterizing the virus family Arenaviridae, established in 1970. In . . . [Full Text of this Article]

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Dr. Peters is a professor of tropical and emerging virology and director of biodefense at the Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston.

Related Letters:

LCMV Transmission by Organ Transplantation
Barton L. L., Sauter C., Sauter B. V., Peters C.J.
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N Engl J Med 2006; 355:1737-1738, Oct 19, 2006. Correspondence

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